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| Status |
Public on Mar 03, 2016 |
| Title |
A549 Gene Expression Following Treatment with a No-Observed-Effect Level of Cisplatin |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We compared the gene expression of A549 cells following 24 and 48 hours of treatment with a no-observed-effect level dose of cisplatin. The objective of the study is to identify genes that are differentially expressed in response to sub-lethal doses of cisplatin. This study helps identify not only treatment responses but also changes in gene expression that may confer cytoprotective mechanisms that allow these cells to survive treatment and to develop treatment resistance.
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| |
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| Overall design |
A total of 12 samples were analyzed with two time points (24 and 48h treatments) and three replicates per condition (treated vs. untreated).
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| |
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| Contributor(s) |
Leung AW, Hung S, Qadir MA, Steidl C, Bally MB |
| Citation(s) |
26938915 |
| |
| Submission date |
Sep 22, 2015 |
| Last update date |
Feb 18, 2019 |
| Contact name |
Ada Leung |
| E-mail(s) |
aleung@bccrc.ca
|
| Organization name |
BC Cancer Research Centre
|
| Department |
Experimental Therapeutics
|
| Street address |
675 West 10th Avenue
|
| City |
Vancouver |
| State/province |
British Columbia |
| ZIP/Postal code |
V5Z 1L3 |
| Country |
Canada |
| |
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| Platforms (1) |
| GPL5175 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version] |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA296561 |
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