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| Status |
Public on Aug 23, 2018 |
| Title |
The differential gene expression in carcinoma-associated fibroblasts co-cultured with MCF7 cells before and after letrozole treatment |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We generated carcinoma-associated fibroblast (CAF) primary cultures from 6 patients with estrogen receptor positive invasive ductal breast carcinoma, co-cultured them with MCF7 cells in estrogen-deprived culture medium and compared their gene expression profiles before and after letrozole treatment. We observed distinct changes in the gene expression profile of CAFs co-cultured with MCF7 cells after letrozole treatment.
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| |
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| Overall design |
Total RNA obtained from carcinoma-associated fibroblasts.
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| |
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| Contributor(s) |
Kang H, Li K |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Aug 24, 2015 |
| Last update date |
Aug 24, 2018 |
| Contact name |
wang li yong |
| E-mail(s) |
wly0410@163.com
|
| Phone |
86-010-83950024
|
| Organization name |
Capital Medical University
|
| Department |
medical school
|
| Lab |
medical lab
|
| Street address |
No 10 xi tou tiao, you an gate
|
| City |
Peking |
| State/province |
Peking |
| ZIP/Postal code |
100069 |
| Country |
China |
| |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (12)
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|
| Relations |
| BioProject |
PRJNA293688 |
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