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Status |
Public on Jan 06, 2023 |
Title |
CPI-0610, a potent and selective BET bromodomain inhibitor optimized for clinical development |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
SUDHL5 cells were treated with DMSO or 2.5 μM CPI203 for 4 hours, then processed for ChIP-Seq to obtain genome-wide binding changes for BRD4 upon treatment with a BET inhibitor.
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Overall design |
Examination of BRD4 binding in the absence or presence of a BET inhibitor in SUDHL5 DLBCL cell line using ChIP-Seq
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Contributor(s) |
Follmer NE, Hatton C, Bryant B, Sims III RJ |
Citation missing |
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Submission date |
Aug 05, 2015 |
Last update date |
Jan 07, 2023 |
Contact name |
Barbara M Bryant |
E-mail(s) |
barbara.bryant@constellationpharma.com
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Organization name |
Constellation Pharmaceuticals
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Street address |
215 First Street
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City |
Cambridge |
State/province |
MA |
ZIP/Postal code |
02142 |
Country |
USA |
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Platforms (1) |
GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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Samples (4)
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Relations |
BioProject |
PRJNA292017 |
SRA |
SRP062069 |