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| Status |
Public on Aug 07, 2015 |
| Title |
Intrahepatic transcriptional signature associated with response to interferon-a treatment in the woodchuck model of chronic hepatitis B |
| Organism |
Marmota monax |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To define the intrahepatic cellular and molecular characteristics of the antiviral response to wIFN-alpha in woodchuck, the transcriptional profiles of woodchuck liver were studied by using RNASeq
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| Overall design |
Woodchucks liver samples with chronic woodchuck hepatitis virus (WHV) infection were treated with recombinant woodchuck IFN-alpha or with placebo for 26 weeks
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| Contributor(s) |
Fletcher SP, Chin DJ, Gruenbaum L, Bitter H, Rasmussen E, Ravindran P, Swinney DC, Birzele F, Schmucki R, Lorenz S, Kopetzki E, Carter J, Triyatni M, Thampi LM, Yang J, AlDeghaither D, Murredu MG, Cote P, Menne S |
| Citation(s) |
26352406 |
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| Submission date |
Jul 31, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Roland Schmucki |
| E-mail(s) |
roland.schmucki@roche.com
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| Organization name |
F. Hoffmann - La Roche AG
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| Street address |
Grenzacherstrase
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| City |
Basel |
| ZIP/Postal code |
4058 |
| Country |
Switzerland |
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| Platforms (1) |
| GPL20757 |
Illumina HiSeq 2500 (Marmota monax) |
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| Samples (203)
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| Relations |
| BioProject |
PRJNA291589 |
| SRA |
SRP061879 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE71582_RAW.tar |
23.6 Mb |
(http)(custom) |
TAR (of TXT) |
| GSE71582_WoodchuckIlluminaTrinity_cap3combined_allbatches.fasta.gz |
76.6 Mb |
(ftp)(http) |
FASTA |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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