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| Status |
Public on Jul 29, 2015 |
| Title |
Gene expression of rat cerebellum in a new animal model of hepatic encephalopathy (HE) |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Identify differentially expressed genes related to the neurodegenerative process in a new animal model of hepatic encephalopathy (HE).
The animal model consists on the simulation of several bouts of HE in PCA rats, being the precipitant factors of the episodes ammonia (NH3) and/or lipopolisaccharide (LPS) or saline.
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| Overall design |
Regular administration (one every two weeks up to 10 infussion) of NH3 (20 μl/min along 3h) and/or LPS (5mg/kg) or in PCA rats. Sham rats were used as a surgery control.
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| Contributor(s) |
Romero J, García T, Chavarria L |
| Citation(s) |
27154504 |
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| Submission date |
Jul 28, 2015 |
| Last update date |
Mar 14, 2017 |
| Contact name |
Teresa García-Lezana |
| E-mail(s) |
teresa.garcia.lezana@vhir.org
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| Organization name |
Vall d'Hebron Research Institute
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| Street address |
Paseo de la Vall d'hebron 119-129
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| City |
Barcelona |
| ZIP/Postal code |
08035 |
| Country |
Spain |
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| Platforms (1) |
| GPL11534 |
[RaGene-1_1-st] Affymetrix Rat Gene 1.1 ST Array [transcript (gene) version] |
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| Samples (24)
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| GSM1834049 |
Rat cerebellum, Sham, sample 4 |
| GSM1834050 |
Rat cerebellum, Sham, sample 5 |
| GSM1834051 |
Rat cerebellum, PCA, sample 1 |
| GSM1834052 |
Rat cerebellum, PCA, sample 2 |
| GSM1834053 |
Rat cerebellum, PCA, sample 3 |
| GSM1834054 |
Rat cerebellum, PCA, sample 4 |
| GSM1834055 |
Rat cerebellum, PCA, sample 5 |
| GSM1834056 |
Rat cerebellum, PCA+NH3, sample 1 |
| GSM1834057 |
Rat cerebellum, PCA+NH3, sample 2 |
| GSM1834058 |
Rat cerebellum, PCA+NH3, sample 3 |
| GSM1834059 |
Rat cerebellum, PCA+NH3, sample 4 |
| GSM1834060 |
Rat cerebellum, PCA+NH3, sample 5 |
| GSM1834061 |
Rat cerebellum, PCA+LPS, sample 1 |
| GSM1834062 |
Rat cerebellum, PCA+LPS, sample 2 |
| GSM1834063 |
Rat cerebellum, PCA+LPS, sample 3 |
| GSM1834064 |
Rat cerebellum, PCA+LPS, sample 4 |
| GSM1834065 |
Rat cerebellum, PCA+LPS, sample 5 |
| GSM1834066 |
Rat cerebellum, PCA+NH3+LPS, sample 1 |
| GSM1834067 |
Rat cerebellum, PCA+NH3+LPS, sample 2 |
| GSM1834068 |
Rat cerebellum, PCA+NH3+LPS, sample 3 |
| GSM1834069 |
Rat cerebellum, PCA+NH3+LPS, sample 4 |
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| Relations |
| BioProject |
PRJNA291186 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE71425_RAW.tar |
106.7 Mb |
(http)(custom) |
TAR (of CEL) |
| GSE71425_normalized_data_with_annotation.txt.gz |
773.1 Kb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
| Processed data are available on Series record |
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