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| Status |
Public on Dec 02, 2015 |
| Title |
Molecular distinctions between proprioceptors supplying Tibialis anterior (TA) and Gastrocnemius (GS) muscles [RNA-Seq] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Muscle-specific populations of proprioceptive sensory neurons form selective connections with spinal motor neurons, implying the existence of molecular distinctions between proprioceptor subpopulations. Here, we compare the gene expression profiles of proprioceptors that supply an antagonistic muscle pair functioning at a single hindlimb joint.
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| Overall design |
TA and GS muscles in a Pv::YFP reporter line were injected at p0 with ctb-555; retrogradely labeled proprioceptors were manually isolated at p1 and pooled to form 25-30 neuron samples.
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| Contributor(s) |
Poliak S, Norovich A, Jessell T |
| Citation missing |
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| |
| Submission date |
Jul 17, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Sebastian Poliak |
| Organization name |
Columbia University
|
| Department |
Neuroscience and Biochemistry and Molecular Biophysics
|
| Lab |
Thomas Jessell
|
| Street address |
701 West 168st
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10032 |
| Country |
USA |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE71029 |
Molecular distinctions between proprioceptors supplying Tibialis anterior (TA) and Gastrocnemius (GS) muscles |
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| Relations |
| BioProject |
PRJNA290148 |
| SRA |
SRP061260 |
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