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| Status |
Public on Jul 11, 2016 |
| Title |
Interferon-alpha signaling promotes AGM HSC maturation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Interferon-alpha promotes engraftment of mid-gestation hematopoietic stem cells by promoting competitiveness and restore the hematopoietic defect of Arid3a knockout embryos
We used microarray to response of AGM HSCs (VE+CD45+) to IFNa (0.5ng/ml) treatment for 4 hours
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| Overall design |
Isolated VE+CD45+ cells from E11.5 AGM were treated with IFNa (0.5ng/ml) in 10% FBS/IMDM for 4 horus before RNA isolation. RNA was NuGen amplified.
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| Contributor(s) |
Kim PG, Daley GQ |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jul 14, 2015 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Peter Geon Kim |
| Organization name |
Dana Farber Cancer Institute
|
| Department |
Hematology/Oncology
|
| Lab |
Ben Ebert
|
| Street address |
360 Longwood Ave, Lc8202
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02215 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (5)
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| Relations |
| BioProject |
PRJNA289751 |
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