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Series GSE70458 Query DataSets for GSE70458
Status Public on Jul 02, 2019
Title Analysis of MACC1 dependent gene expression regulation in CRC cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We employed whole genome expression profiling to identify differential gene expression in the colorectal cancer (CRC) cell line SW480 (ATCC - CCL-228), dependent on the expression level of MACC1 (Metastasis Associated in Colon Cancer 1). SW480 cells with endogenously low expression levels of MACC1 were transfected either with CMV-promoter driven MACC1-cDNA or the empty vector, and selected for stable expression.
 
Overall design Total RNA of two biological replicates of both MACC1 overexpressing cells and vector control cells, respectively, was isolated and subjected to whole genome expression profiling.
 
Contributor(s) Schmid F, Wang Q
Citation(s) 26686083
Submission date Jul 01, 2015
Last update date Jul 02, 2019
Contact name Mathias Dahlmann
E-mail(s) mathias@kaddea.de
Phone +49 30 9406 2389
Organization name Charité University Medicine
Department Experimental and Clinical Research Center
Lab Translational Oncology of Solid Tumors
Street address Robert-Rössle-Str. 10
City Berlin
ZIP/Postal code 13125
Country Germany
 
Platforms (1)
GPL4133 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
Samples (4)
GSM1755160 macc1_1
GSM1755161 macc1_2
GSM1755162 control_1
Relations
BioProject PRJNA288718

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE70458_Normalized_data_with_probename.txt.gz 1.3 Mb (ftp)(http) TXT
GSE70458_RAW.tar 33.7 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table
Processed data are available on Series record

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