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Status |
Public on Jul 02, 2019 |
Title |
Analysis of MACC1 dependent gene expression regulation in CRC cells |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
We employed whole genome expression profiling to identify differential gene expression in the colorectal cancer (CRC) cell line SW480 (ATCC - CCL-228), dependent on the expression level of MACC1 (Metastasis Associated in Colon Cancer 1). SW480 cells with endogenously low expression levels of MACC1 were transfected either with CMV-promoter driven MACC1-cDNA or the empty vector, and selected for stable expression.
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Overall design |
Total RNA of two biological replicates of both MACC1 overexpressing cells and vector control cells, respectively, was isolated and subjected to whole genome expression profiling.
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Contributor(s) |
Schmid F, Wang Q |
Citation(s) |
26686083 |
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Submission date |
Jul 01, 2015 |
Last update date |
Jul 02, 2019 |
Contact name |
Mathias Dahlmann |
E-mail(s) |
mathias@kaddea.de
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Phone |
+49 30 9406 2389
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Organization name |
Charité University Medicine
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Department |
Experimental and Clinical Research Center
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Lab |
Translational Oncology of Solid Tumors
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Street address |
Robert-Rössle-Str. 10
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City |
Berlin |
ZIP/Postal code |
13125 |
Country |
Germany |
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Platforms (1) |
GPL4133 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
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Samples (4)
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Relations |
BioProject |
PRJNA288718 |