|
| Status |
Public on Jul 15, 2015 |
| Title |
PRMT5 is essential for sustaining normal adlut hematopoiesis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Examining the effects of PRMT5 loss on the gene expression profile of hematopoietic stem and progenitor cells
|
| |
|
| Overall design |
We established the PRMT5 conditional KO mice, and bred the mice with Mx1 cre transgenic mice to delete PRMT5 in hematopoietic cells. We isolated hematopoetic stem and progenitor cells 3 days after PRMT5 deletion, and examined the gene expression files using RNA-sequencing.
|
| |
|
| Contributor(s) |
Liu F, Nimer SD |
| Citation(s) |
26258414 |
| |
| Submission date |
Jun 16, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Fan Liu |
| E-mail(s) |
fliu@med.miami.edu
|
| Phone |
3052430885
|
| Organization name |
University of Miami
|
| Department |
Biochemistry and Molecular Biology
|
| Lab |
Stephen Nimer
|
| Street address |
1501 NW 10th Ave
|
| City |
Miami |
| State/province |
Florida |
| ZIP/Postal code |
33136 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA287164 |
| SRA |
SRP059561 |
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