|
| Status |
Public on Apr 04, 2016 |
| Title |
Transcriptome and Micronome analysis of OPLL |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
Ossification of the posterior longitudinal ligament (OPLL) is formed by heterogeneous ossification of posterior longitudinal ligament. The patho-mechanism of OPLL is still largely unknown. MicroRNAs are small nucleatides that function as regulators of gene expression in almost any biological process. However, few microRNAs are reported to have a role in the pathological process of OPLL. Therefore, we performed high-throughput microRNA sequencing and transcriptome sequencing of primary OPLL and PLL cells in order to decipher the interacting network of microRNAs in OPLL.
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| |
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| Overall design |
MRNA and microRNA profiles were done using primary culture cells of human ossification of the posterior longitudinal ligament (OPLL) tissue and normal posterior longitudinal ligament (PLL) tissue.
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| |
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| Contributor(s) |
Xu C, Liu Y |
| Citation(s) |
26868491 |
| |
| Submission date |
Jun 11, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Chen Xu |
| E-mail(s) |
chenxu8836@hotmail.com
|
| Phone |
+86-13774294166
|
| Organization name |
The Second Military Medical University
|
| Street address |
No, 800, Rd. Xiangyin
|
| City |
Shanghai |
| ZIP/Postal code |
200433 |
| Country |
China |
| |
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| Platforms (1) |
| GPL17303 |
Ion Torrent Proton (Homo sapiens) |
|
| Samples (12)
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| Relations |
| BioProject |
PRJNA286783 |
| SRA |
SRP059380 |
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