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Series GSE69787 Query DataSets for GSE69787
Status Public on Apr 04, 2016
Title Transcriptome and Micronome analysis of OPLL
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
Summary Ossification of the posterior longitudinal ligament (OPLL) is formed by heterogeneous ossification of posterior longitudinal ligament. The patho-mechanism of OPLL is still largely unknown. MicroRNAs are small nucleatides that function as regulators of gene expression in almost any biological process. However, few microRNAs are reported to have a role in the pathological process of OPLL. Therefore, we performed high-throughput microRNA sequencing and transcriptome sequencing of primary OPLL and PLL cells in order to decipher the interacting network of microRNAs in OPLL.
 
Overall design MRNA and microRNA profiles were done using primary culture cells of human ossification of the posterior longitudinal ligament (OPLL) tissue and normal posterior longitudinal ligament (PLL) tissue.
 
Contributor(s) Xu C, Liu Y
Citation(s) 26868491
Submission date Jun 11, 2015
Last update date May 15, 2019
Contact name Chen Xu
E-mail(s) chenxu8836@hotmail.com
Phone +86-13774294166
Organization name The Second Military Medical University
Street address No, 800, Rd. Xiangyin
City Shanghai
ZIP/Postal code 200433
Country China
 
Platforms (1)
GPL17303 Ion Torrent Proton (Homo sapiens)
Samples (12)
GSM1708774 PLL-1 mRNA
GSM1708775 PLL-2 mRNA
GSM1708776 PLL-3 mRNA
Relations
BioProject PRJNA286783
SRA SRP059380

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE69787_RNA_All_Counts.txt.gz 379.8 Kb (ftp)(http) TXT
GSE69787_miRNA_All_Counts.txt.gz 50.9 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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