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Series GSE69470 Query DataSets for GSE69470
Status Public on Aug 01, 2015
Title microRNA expression profiling of human sarcoma cell lines (~68) in the Molecular Pharmacology Branch, DTP, DCTD NCI collection of human cell lines
Organism Homo sapiens
Experiment type Non-coding RNA profiling by array
Summary Characterization of ~68 cell lines derived from human sarcoma and 5 normal counterpart cells, including drug sensitivity testing, gene expression profiling and microRNA expression profiling have been completed. Data and tools for searching these data will be made publicly available through the NCI Developmental Therapeutics Program. The raw data (RCC files) are provided through the GEO website. Sarcoma represents a variety of cancers at arise from cells of mesenchymal origin and have seen limited treatment advances in the last decade. Drug sensitivity data coupled with the transcription and microRNA profiles of a cohort of sarcoma cell lines may help define novel treatment paradigms.
 
Overall design For each cell line, microRNA expression was measured on nCounter miRNA Expression Arrays (Nanostring Technologies), providing multiplexed, digital detection and counting of 800 human microRNA's.

Please note that there are 2 replicates included in the study:
A-204-rep1 and A-204-rep2, ES-4-rep1 and ES-4-rep2 resulting total 77 samples.
 
Contributor(s) Monks A, Polley E, Teicher B
Citation(s) 26351324
Submission date Jun 02, 2015
Last update date Sep 11, 2015
Contact name Eric C Polley
E-mail(s) eric.polley@nih.gov
Organization name National Cancer Institute
Department Biometric Research Branch
Street address 9609 Medical Center Drive, Rm 5W118
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
 
Platforms (1)
GPL20275 NanoString nCounter Human miRNA Expression Assay v2 [mRNA ID]
Samples (77)
GSM1701622 A-204 [miRNA]
GSM1701623 A-673 [miRNA]
GSM1701624 ASPS-1 [miRNA]
This SubSeries is part of SuperSeries:
GSE69524 NCI Sarcoma Cell Line Panel
Relations
BioProject PRJNA285892

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE69470_RAW.tar 590.0 Kb (http)(custom) TAR (of RCC)
Processed data included within Sample table

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