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| Status |
Public on Aug 03, 2015 |
| Title |
Allelome.PRO A pipeline to define allele-specific genome features |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We used RNA-seq data from mouse embryonic fibroblasts from F1 reciprocal crosses to determine a biologically relevant allelic ratio cutoff, and define for the first time an entire allelome. Furthermore, we show that Allelome.PRO detects differential enrichment of H3K4me3 over promoters from ChIP-seq data validating the RNA-seq results.
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| |
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| Overall design |
Defining allele-specific genome features from F1 E12.5 mouse embryonic fibroblasts
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| |
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| Contributor(s) |
Andergassen D, Dotter CP, Hudson QJ, Pauler FM |
| Citation(s) |
26202974 |
| |
| Submission date |
May 22, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Daniel Andergassen |
| Organization name |
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
|
| Lab |
Barlow
|
| Street address |
Lazarettgasse 14, AKH BT 25.3
|
| City |
Vienna, Austria |
| ZIP/Postal code |
A-1090 |
| Country |
Austria |
| |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA284740 |
| SRA |
SRP058631 |
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