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| Status |
Public on Mar 11, 2016 |
| Title |
Expression data from Saccharomyces cerevisae strains overexpressing RNA-binding hnRNP Yra1 |
| Platform organisms |
Schizosaccharomyces pombe; Saccharomyces cerevisiae |
| Sample organism |
Saccharomyces cerevisiae |
| Experiment type |
Expression profiling by array
|
| Summary |
Transcription is a major obstacle for replication fork progression and a cause of genome instability. Such instability increases in mutants with an imbalance proportion of Yra1, a component of THO/TREX.
We used microarrays to the global impact of Yra1 overexpression and found that no general impact was observed.
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| Overall design |
S. cerevisiae strains were grown in minimal medium raffinose and were shifted to galactose (2%) for four hours in liquid culture, total RNA was isolated and hybridized on Affymetrix microarrays
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| Contributor(s) |
Gavaldá S, Santos-Pereira JM, García-Rubio ML, Luna R, Aguilera A |
| Citation(s) |
27035147 |
| Submission date |
May 04, 2015 |
| Last update date |
Feb 21, 2017 |
| Contact name |
Andrés Aguilera |
| Organization name |
CABIMER, Universidad de Sevilla
|
| Department |
Genome BIology
|
| Lab |
Genome Instability & Cancer
|
| Street address |
Av. Américo Vespucio 24
|
| City |
Seville |
| ZIP/Postal code |
41092 |
| Country |
Spain |
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| Platforms (1) |
| GPL2529 |
[Yeast_2] Affymetrix Yeast Genome 2.0 Array |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE68488 |
YRA1 overexpression microarray and ChIP-chip |
|
| Relations |
| BioProject |
PRJNA282920 |
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