|
| Status |
Public on Apr 30, 2016 |
| Title |
Placebo-controlled, randomized clinical trial with repeated liver biopsies: Long-term resveratrol treatment has no clear therapeutic benefit in non-alcoholic fatty liver disease |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Resveratrol treatment has shown beneficial effects on experimental models of non-alcoholic liver disease (NAFLD). In this pilot-size, clinical trial we teated the therapeutic potential in NAFLD patients.
We found only limited clinical effect of resveratrol treatment.
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| |
|
| Overall design |
Prospective, placebo-controlled, randomized clinical trial with two treatment arms: resveratrol 1.5 g daily (RSV) or placebo (Plc) for 6 months. Participants had baseline and end-of-trial biopsies performed.
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| |
|
| Contributor(s) |
Heebøll S, Grønbæk H |
| Citation(s) |
26784973 |
| |
| Submission date |
Apr 29, 2015 |
| Last update date |
Mar 15, 2019 |
| Contact name |
Kasper Thorsen |
| E-mail(s) |
kasper.thorsen@ki.au.dk
|
| Organization name |
Aarhus University Hospital
|
| Street address |
Brendstrupgaardsvej
|
| City |
Aarhus |
| ZIP/Postal code |
8200 |
| Country |
Denmark |
| |
|
| Platforms (1) |
| GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
|
| Samples (32)
|
|
| Relations |
| BioProject |
PRJNA282686 |
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