|
| Status |
Public on Oct 24, 2015 |
| Title |
Expression data of mouse NIH3T3 and NIH3T3-k-ras transformed cell lines after Forskolin treatment |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Forskolin treatment induces activation of protein kinase A. This activation protects transformed cells from death induced by glucose starvation.
We used microarray to identify the mechanisms involved in such a pro-survival effect.
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| |
|
| Overall design |
NIH3T3 and NIH3T3-K-ras were plated at 1mM glucose and then daily treated or not with 10uM FSK until 72h of growth. The microarray analysis has been performed at 72h in order to identify specific mechanisms associate with transformed cells survival.
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| |
|
| Contributor(s) |
Chiaradonna F, Pirola Y, Palorini R |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Apr 24, 2015 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Ferdinando Chiaradonna |
| E-mail(s) |
ferdinando.chiaradonna@unimib.it
|
| Phone |
+39-02-64483526
|
| Organization name |
University of Milano-Bicocca
|
| Department |
Biotechnology and Biosciences
|
| Street address |
Piazza della scienza, 2
|
| City |
Milan |
| ZIP/Postal code |
20126 |
| Country |
Italy |
| |
|
| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (12)
|
| GSM1666885 |
NIH3T3 at 72h no FSK biological replicate 1 |
| GSM1666886 |
NIH3T3 at 72h no FSK biological replicate 2 |
| GSM1666887 |
NIH3T3 at 72h no FSK biological replicate 3 |
| GSM1666888 |
NIH3T3-Kras at 72h no FSK biological replicate 1 |
| GSM1666889 |
NIH3T3-Kras at 72h no FSK biological replicate 2 |
| GSM1666890 |
NIH3T3-Kras at 72h no FSK biological replicate 3 |
| GSM1666891 |
NIH3T3 at 72h+FSK biological replicate 1 |
| GSM1666892 |
NIH3T3 at 72h+FSK biological replicate 2 |
| GSM1666893 |
NIH3T3 at 72h+FSK biological replicate 3 |
| GSM1666894 |
NIH3T3-Kras at 72h+FSK biological replicate 1 |
| GSM1666895 |
NIH3T3-Kras at 72h+FSK biological replicate 2 |
| GSM1666896 |
NIH3T3-Kras at 72h+FSK biological replicate 3 |
|
| Relations |
| BioProject |
PRJNA282157 |
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