|
| Status |
Public on Apr 27, 2015 |
| Title |
Effects of Trbp deletion on gene expession in mice hearts |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
We generated the cardiac-specific knockout of Trbp (Trbp-cKO) in mice. We profiled the transcriptome in both wild-type and Trbp-cKO hearts, and found numerous genes were deregulated by deletion of Trbp. We also profiled miRNA expression both wild-type and Trbp-cKO hearts, and found expression of a subset of miRNA species was altered in Trbp-cKO hearts.
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| |
|
| Overall design |
Examine expression of mRNAs and miRNAs in wild-type and Trbp-cKO hearts
|
| |
|
| Contributor(s) |
Ding J, Wang Y, Wang D |
| Citation(s) |
26029872 |
| |
| Submission date |
Apr 08, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Da-Zhi Wang |
| E-mail(s) |
dwang@enders.tch.harvard.edu
|
| Phone |
617-919-4768
|
| Organization name |
Boston Children's Hospital
|
| Department |
Cardiology
|
| Street address |
300 Longwood Ave.
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (10)
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|
| Relations |
| BioProject |
PRJNA280580 |
| SRA |
SRP056963 |
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