|
| Status |
Public on Jul 27, 2015 |
| Title |
Impact of Lef1 overexpression on follicular helper T (Tfh) differentiation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Comparison of transcriptome between GFP-RV+ Th1 cells and Lef1-RV+ Th1 cells
|
| |
|
| Overall design |
B6 mice received GFP-RV+ or Lef1-RV+ LCMV gp specific TCRtg Smarta cells and were infected with LCMV. On four days after infection, splenocytes were collected to sort CXCR5- Th1 cells per genotype. Contributor: LIAI RNAi Center (LIAI)
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| |
|
| Contributor(s) |
Crotty S |
| Citation(s) |
26214741 |
| |
| Submission date |
Mar 26, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Shane Crotty |
| E-mail(s) |
shane@liai.org
|
| Organization name |
La Jolla Institute for Allergy and Immunology
|
| Street address |
9420 Athena Circle
|
| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92037 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (4)
|
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| This SubSeries is part of SuperSeries: |
| GSE67336 |
LEF-1 and TCF-1 orchestrate T follicular helper (Tfh) cell differentiation by regulating Tfh differentiation circuits upstream of Bcl6 |
|
| Relations |
| BioProject |
PRJNA279530 |
| SRA |
SRP056606 |
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