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Series GSE67335 Query DataSets for GSE67335
Status Public on Jul 27, 2015
Title Impact of Lef1 overexpression on follicular helper T (Tfh) differentiation
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Comparison of transcriptome between GFP-RV+ Th1 cells and Lef1-RV+ Th1 cells
Overall design B6 mice received GFP-RV+ or Lef1-RV+ LCMV gp specific TCRtg Smarta cells and were infected with LCMV. On four days after infection, splenocytes were collected to sort CXCR5- Th1 cells per genotype. Contributor: LIAI RNAi Center (LIAI)
Contributor(s) Crotty S
Citation(s) 26214741
Submission date Mar 26, 2015
Last update date May 15, 2019
Contact name Shane Crotty
Organization name La Jolla Institute for Allergy and Immunology
Street address 9420 Athena Circle
City La Jolla
State/province CA
ZIP/Postal code 92037
Country USA
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (4)
GSM1645008 LEF1_TH1_Rep1
GSM1645009 LEF1_TH1_Rep2
GSM1645010 pMIG_TH1_Rep1
This SubSeries is part of SuperSeries:
GSE67336 LEF-1 and TCF-1 orchestrate T follicular helper (Tfh) cell differentiation by regulating Tfh differentiation circuits upstream of Bcl6
BioProject PRJNA279530
SRA SRP056606

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE67335_LEF1_Th1.Vs.pMIG_Th1.DESeq_Analysis_DE_Genes.txt.gz 540.8 Kb (ftp)(http) TXT
GSE67335_LEF1_Th1.Vs.pMIG_Th1.DESeq_ReadsCount.txt.gz 154.3 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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