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| Status |
Public on Mar 05, 2015 |
| Title |
Expression data from CSC and Non-CSC of three HCC cell lines |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Hepatocellular carcinoma (HCC) represents the major subtype of liver cancer, characterized with a high rate of recurrence and heterogeneity. Liver cancer stem cells (CSCs) may account for a hierarchical organization of heterogeneous cancer cells. However, how liver CSCs sustain their self-renewal remains largely unknown.
We used microarrays to discover the long non-coding RNAs (lncRNAs) expression underlying cell stem cell (CSC) and non cell stem cell (non-CSC) and identified distinct lncRNAs during this process.
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| Overall design |
We sorted CD13+CD133+ and CD13-CD133- cells from Hep3B, Huh7, and PLC/PRF/5 HCC cell lines as liver CSCs and non-CSCs, then hybridized on Affymetrix microarrays. We sought to identify distinct lncRNAs in liver CSCs.
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| Contributor(s) |
Wang Y |
| Citation(s) |
25842979 |
| |
| Submission date |
Mar 04, 2015 |
| Last update date |
Mar 15, 2019 |
| Contact name |
Yanying Wang |
| E-mail(s) |
wangyanying@moon.ibp.ac.cn
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| Organization name |
Institute of Biophysics, Chinese Academy of Sciences
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| Street address |
15 Datun Road, Chaoyang District,Beijing 100101, China
|
| City |
Beijing |
| ZIP/Postal code |
100101 |
| Country |
China |
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| Platforms (1) |
| GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA277212 |
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