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Series GSE65808 Query DataSets for GSE65808
Status Public on Dec 01, 2015
Title Combining ChIP-Seq and RNA-Seq data in early placental development to study trophoblast invasion [RNA-Seq]
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary The placenta is an understudied organ that has a critical role in mammalian development. In early placental development, the essential process of trophoblast invasion establishes adequate blood flow between mother and fetus. Despite its importance, little is known about the genomic regions responsible for regulating trophoblast invasion. In order to identify enhancers that are important for regulating the process, we carried out ChIP-Seq for an enhancer-associated mark at two time points during early placental development. Combining these data with RNA-Seq data and protein interaction data allowed us to construct a gene-enhancer network describing trophoblast invasion.
Overall design RNA-Seq at two time points in early placenta development (e7.5 an e9.5). There are 3 biological replicates per time point. Samples were pooled and sequenced on two lanes.
Contributor(s) Tuteja G
Citation(s) 26604129
Submission date Feb 10, 2015
Last update date May 15, 2019
Contact name Geetu Tuteja
Organization name Iowa State University
Department Genetics, Development and Cell Biology
Street address 2106 Molecular Biology Building
City Ames
State/province IA
ZIP/Postal code 50011
Country USA
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (6)
GSM1606640 e7.5 EPC RNA-Seq (1)
GSM1606641 e7.5 EPC RNA-Seq (2)
GSM1606642 e7.5 EPC RNA-Seq (3)
This SubSeries is part of SuperSeries:
GSE65809 Combining ChIP-Seq and RNA-Seq data in early placental development to study trophoblast invasion
BioProject PRJNA275121
SRA SRP053433

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE65808_allReplicate_FPKMs.txt.gz 1.5 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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