|
| Status |
Public on Jan 22, 2015 |
| Title |
Gene array analysis of anaplastic thyroid carcinoma tissue versus matched and unmatched normal thyroid tissue |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Currently there is a lack of effective therapies which result in long-term durable response for patients presenting with anaplastic thyroid carcinoma (ATC), a very rare and lethal variant of thyroid cancer. ATC is resistant to chemotherapy, radiation, and targeted therapies currently available. In an effort to identify novel tumor-specific therapeutic targets, we performed high throughput gene array analysis screening numerous patient ATC tumor tissues, and compared their gene expression levels to matched and unmatched normal thyroid tissue samples.
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| |
|
| Overall design |
RNA was extracted from flash frozen patient tumor and normal samples. Gene array analysis was performed, and resulting expression levels were compared between normal and tumor samples.
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| |
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| Contributor(s) |
von Roemeling CA, Copland JA, Tun HW |
| Citation(s) |
25675381 |
| |
| Submission date |
Jan 21, 2015 |
| Last update date |
Mar 25, 2019 |
| Contact name |
John A Copland |
| Organization name |
The Mayo Clinic, Jacksonville FL
|
| Department |
Cancer Research
|
| Lab |
Copland Lab
|
| Street address |
4500 San Pablo Rd
|
| City |
Jacksonville |
| State/province |
Florida |
| ZIP/Postal code |
32224 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (25)
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| Relations |
| BioProject |
PRJNA273276 |
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