|
| Status |
Public on Jan 17, 2015 |
| Title |
Plasma profiling of miRNAs in human specimens from osteosarcoma patients. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by RT-PCR
|
| Summary |
Osteosarcoma (OS) is the primary bone tumor in children and young adults. Currently, there are no reliable, non-invasive biological markers to detect the presence or progression of disease, assess therapy response, or provide upfront prognostic insights. Using a qPCR-based platform that analyzes more than 750 miRNAs, we analyzed control and diseased-associated plasma from human cases of OS to identify a profile of differentially expressed miRNAs.
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| |
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| Overall design |
Comprehensive miRNA expression profiling was completed using the Exiqon miRNome platform (human panels I+II, V3) on 20 disease samples (10 localized, 10 metastatic) and 15 healthy controls.
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| |
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| Contributor(s) |
Yustein J, Allen-Rhoades W |
| Citation(s) |
25784290 |
| |
| Submission date |
Jan 16, 2015 |
| Last update date |
Apr 25, 2016 |
| Contact name |
Chad Creighton |
| E-mail(s) |
creighto@bcm.tmc.edu
|
| Organization name |
Baylor College of Medicine
|
| Department |
Biostatistics, Ducan Cancer Center
|
| Street address |
One Baylor Plaza, Mail Stop: BCM305
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL19631 |
Exiqon human V3 microRNA PCR panel I+II |
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| Samples (35)
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| Relations |
| BioProject |
PRJNA272827 |
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