|
| Status |
Public on Sep 08, 2016 |
| Title |
Transcriptional profiling of E14.5 control and Tbr2 fl/fl;Foxg1::Cre cortices |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The abscence of TBR2 gene in human leads to microcephaly. This condition is mimicked by the specific ablation of the murine gene in developing cerebral cortex. Herein we compared gene expression in control and Tbr2 cKO in E14.5 cerebral cortices. This approach represents a useful tool to identify the molecular mechanisms at the basis of the phenotype.
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| |
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| Overall design |
6 samples, 3x Tbr2 +/+;Foxg1::Cre (control) and 3x Tbr2 fl/fl;Foxg1::Cre
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| |
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| Contributor(s) |
Sessa A, Massimino L, Broccoli V |
| Citation(s) |
27600842 |
| |
| Submission date |
Nov 25, 2014 |
| Last update date |
Jan 16, 2019 |
| Contact name |
Luca Massimino |
| E-mail(s) |
admin@lucamassimino.com
|
| Phone |
+393389039500
|
| Organization name |
Ospedale San Raffaele
|
| Department |
Gastroenterology
|
| Street address |
Via Olgettina, 58
|
| City |
Milano |
| State/province |
MI |
| ZIP/Postal code |
20100 |
| Country |
Italy |
| |
|
| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
|
| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE63621 |
Tbr2 and Neurog2 occupancy and transcriptional profiling of control and Tbr2 knockout E14.5 cerebral cortices |
|
| Relations |
| BioProject |
PRJNA268487 |
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