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Series GSE62368 Query DataSets for GSE62368
Status Public on Dec 08, 2015
Title Transcript expression in circulating whole blood after saline injections
Organism Rattus norvegicus
Experiment type Expression profiling by high throughput sequencing
Summary These experiments were designed to produce the appropriate controls so that their cohort's transcript (mRNA) changes in whole circulating blood could be determined. The cohorts were exposed to D-amphetamine under a neurotoxic and non-neurotoxic condition or subjected to elevated environmental temperatures that produced a hyperthermia very similar to heat stroke. The cohort data is in a separate, but linked, GEO file.
Overall design Animals were given four doses of 1 ml/ kg of normal saline with two hours in between each dose. The animals body temperature was determined every 1 h and the rats were sacrificed 3 h after the last saline injection. Animals were not given access to food or water during this period so that they were more suitable controls for the amphetamine treatment groups
Contributor(s) Bowyer JF, Crabtree NM, George NI
Citation(s) 26177368
Submission date Oct 15, 2014
Last update date May 15, 2019
Contact name John Francis Bowyer
Phone 870-543-7194
Organization name National Center for Toxicological Research FDA
Department Neurotoxicology
Lab Neurobiology
Street address 3900 NCTR Drive
City Jefferson
State/province AR
ZIP/Postal code 72079-9502
Country USA
Platforms (1)
GPL14844 Illumina HiSeq 2000 (Rattus norvegicus)
Samples (16)
GSM1525849 Control ID ML322
GSM1525850 Control ID JB88
GSM1525851 Control ID JB108
BioProject PRJNA264000
SRA SRP048964

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE62368_RAW.tar 3.0 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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