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Series GSE61769 Query DataSets for GSE61769
Status Public on Sep 26, 2014
Title SNP genotyping data from human iPSCs and human fibroblast cells
Organism Homo sapiens
Experiment type Genome variation profiling by SNP array
Summary Human induced pluripotent stem cells changed the face of stem cell biology as they represent a renewable source of stem cells with the potential to differentiated into multiple lineages in a manner akin to embryonic stem cells that can be collected without the need for the destruction of an embryo. The potential of these cells as research tools is vast as they can be pushed to generate different cell types depending on research interest. Many complex diseasese.g. late onset alzheimer's disease and type 2 diabetes have known genetic risk factors that increase the likelihood of developing a disease. We performed whole genome SNP analysis to examine risk loci for different complex diseases in our donor iPS cells toanalyse disease risk and also assess which donor represents the best healthy background.
Overall design Genomic DNA was isolated from human induced pluripotent stem cells from 3 donors and fibroblasts from an additional donor for genome-wide SNP analysis. This study was completed using the Affymetrix human genome-wide array 6.0 and analysed using the Affymetrix Genotyping Console Birdseed V2 algorithm.
Web link
Contributor(s) Wei J, Cox C, Shi Y
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Submission date Sep 25, 2014
Last update date Nov 27, 2018
Contact name Yichen Shi
Organization name Axol Bioscience Limited
Street address Suite 3, The Science Village Building, Chesterford Research Park, Little Chesterford
City Cambridgeshire
ZIP/Postal code CB10 1XL
Country United Kingdom
Platforms (1)
GPL6801 [GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array
Samples (4)
GSM1513685 human iPSC Axol-015
GSM1513686 human iPSC Axol-016
GSM1513687 human iPSC Axol-C12502
BioProject PRJNA262087

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE61769_Genotypes.txt.gz 41.8 Mb (ftp)(http) TXT
GSE61769_RAW.tar 170.9 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data are available on Series record

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