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Status |
Public on Dec 23, 2014 |
Title |
Transcriptomic response of bovine dermal fibroblasts to lipopolysaccharide |
Organism |
Bos taurus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
We report the responsiveness of bovine dermal fibroblasts to lipopolyssacharide (LPS) within individuals at different ages. Cultures were collected from three different heifers at the ages of approximately 5 and 16 months. Isolated fibroblasts were then exposed to LPS to determine whether there was a differential response within an animal based upon age.
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Overall design |
Fibroblasts were isolated from 3 cows at the ages 5 months and 16 months. Isolated fibroblasts were treated with LPS for 0 hrs, 2 hrs, and 8 hrs.
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Contributor(s) |
Kerr DE, Green BB, McKay SD |
Citation(s) |
25623529 |
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Submission date |
Sep 02, 2014 |
Last update date |
May 15, 2019 |
Contact name |
David E Kerr |
E-mail(s) |
david.kerr@uvm.edu
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Organization name |
University of Vermont
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Department |
Animal Science
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Street address |
500 Main Street 205 Terrill Hall
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City |
Burlington |
State/province |
VT |
ZIP/Postal code |
05401 |
Country |
USA |
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Platforms (1) |
GPL19150 |
Illumina HiSeq 1000 (Bos taurus) |
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Samples (18)
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This SubSeries is part of SuperSeries: |
GSE61168 |
Age-dependent changes in the LPS-induced transcriptome of bovine dermal fibroblasts occurs without major changes in the methylome |
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Relations |
BioProject |
PRJNA260094 |
SRA |
SRP046286 |