|
| Status |
Public on Aug 05, 2014 |
| Title |
Acute (2 hr) response to rxLeptin injection in preoptic area/hypothalamus/pituitary of juvenile Xenopus laevis |
| Organism |
Xenopus laevis |
| Experiment type |
Expression profiling by array
|
| Summary |
Leptin binding to the leptin receptor (LepR) causes rapid signaling to the nucleus. We investigated the early (2 hr) transcriptional response to acute leptin injectio (intracerebroventricular)
in the preoptic area/hypothalamus/pituitary of juvenile Xenopus laevis frogs.
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| |
|
| Overall design |
Frogs were given i.c.v. injections of 0.6% saline or recombinant X. laevis leptin (rxLeptin; 20 ng/g BW) and 2 hrs later killed and the preoptic area/hypothalamus/pituitary dissected.
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| |
|
| Contributor(s) |
Denver RJ, Cui M |
| Citation(s) |
25153147 |
| |
| Submission date |
Aug 04, 2014 |
| Last update date |
Oct 02, 2015 |
| Contact name |
Robert J Denver |
| E-mail(s) |
rdenver@umich.edu
|
| Phone |
7349366625
|
| Organization name |
University of Michigan
|
| Department |
MCDB
|
| Street address |
1105 North University Ave
|
| City |
Ann Arbor |
| State/province |
Michigan |
| ZIP/Postal code |
48109-1085 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10756 |
[X_laevis_2] Affymetrix Xenopus laevis Genome 2.0 Array |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA257392 |
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