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| Status |
Public on Aug 01, 2014 |
| Title |
Circulating miRNA microarray data from breast cancer patients |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
Independent studies have reported that circulating miRNAs have the potential as biomarkers; however, no consolidated guidelines for the discovery process are available. We developed a pipeline using innovative applications of existing bioinformatics methods to (1) face the inapplicability of the classical normalization methods, (2) detect global differences of miRNA distributions between the comparison classes and (3) develop a 'robust’ classifier.
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| Overall design |
78 samples (26 hemolyzed and 52 non hemolyzed) were 1:2 paired with caliper matching according to disease status, age at drawing and drawing year, starting from a total of 208 hybridized samples collected between 1987 and 2004 (including 94 paired samples according to tumor ER status, age at drawing, drawing year, time from surgery, 7 additional samples from 'no evidence of disease' (NED) patients, 10 references, 1 healthy donor and 2 replicated samples)
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| Contributor(s) |
Landoni E |
| Citation(s) |
26581577 |
| |
| Submission date |
Jul 31, 2014 |
| Last update date |
Jul 31, 2019 |
| Contact name |
Elena Landoni |
| E-mail(s) |
elena.landoni@istitutotumori.mi.it
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| Organization name |
Fondazione IRCCS Istituto Nazionale dei Tumori
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| Street address |
Via Vanzetti 5
|
| City |
Milano |
| ZIP/Postal code |
20133 |
| Country |
Italy |
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| Platforms (1) |
| GPL16770 |
Agilent-031181 Unrestricted_Human_miRNA_V16.0_Microarray (miRBase release 16.0 miRNA ID version) |
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| Samples (78)
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| Relations |
| BioProject |
PRJNA257226 |
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