|
| Status |
Public on Jul 01, 2014 |
| Title |
An Integrated Approach to Reconstructing Genome-scale Transcriptional Regulatory Networks [ChIP-Seq] |
| Organism |
Cereibacter sphaeroides 2.4.1 |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
By integrating sequence information from closely related bacteria with a compendium of high-throughput gene expression datasets, a large-scale transcriptional regulatory networks was constructed for Rhodobacter sphaeroides. Predictions from this network were validated in part using genome-wide analysis for 3 transcription factors (PpsR, RSP_0489 and RSP_3341).
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| |
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| Overall design |
Genome-wide protein-DNA interaction analysis of 3 transcription factors predicted to be involved in photosynthesis (PpsR), carbon metabolism (RSP_0489) and iron homeostasis (RSP_3341) were used to validate predictions from a large-scale reconstruction of R. sphaeroides transcriptional regulatory network.
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| |
|
| Contributor(s) |
Imam S, Donohue TJ |
| Citation(s) |
25723545 |
| |
| Submission date |
Jun 19, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Timothy J Donohue |
| E-mail(s) |
tdonohue@bact.wisc.edu
|
| Phone |
608-265-8465
|
| Organization name |
University of Wisconsin - Madison
|
| Department |
Bacteriology
|
| Lab |
Timothy Donohue
|
| Street address |
1552 University Avenue
|
| City |
Madison |
| State/province |
WI |
| ZIP/Postal code |
53726 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL17213 |
Illumina HiSeq 2000 (Rhodobacter sphaeroides 2.4.1) |
| GPL18842 |
Illumina HiSeq 2500 (Rhodobacter sphaeroides 2.4.1) |
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| Samples (4)
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| This SubSeries is part of SuperSeries: |
| GSE58658 |
An Integrated Approach to Reconstructing Genome-scale Transcriptional Regulatory Networks |
|
| Relations |
| BioProject |
PRJNA253093 |
| SRA |
SRP043410 |
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