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| Status |
Public on Jun 17, 2015 |
| Title |
Detection of urinary microRNAs from epithelial ovarian cancer patients as biomarker |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
The Urine RNA from 5 ovarian cancer and 5 healthy control were analyzed with the Human miRNA Microarray and then validated with a quantitative reverse-transcription PCR assay with 29 individual samples, 20 benign gynecological disease and 26 age/sex-matched healthy control. This study determines the clinical value of urine miRNAs as biomarker for epithelial ovarian cancer.
Results: The miRNA microarray results demonstrate that the original 38 were identified that were significantly differentially expression in epithelial ovarian cancer compared with healthy control (P<0.01). A total of 1 miRNA was up-regulated in ovarian cancer, while 37 miRNA were down-regulated.
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| |
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| Overall design |
the urine RNA from 5 ovarian cancer and 5 healthy women were analysised with Human mirRNA microarry
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| |
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| Contributor(s) |
Zhou J, Wu X |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jun 16, 2014 |
| Last update date |
Jun 19, 2015 |
| Contact name |
Jun Zhou |
| Organization name |
urine
|
| Department |
Central South University
|
| Lab |
Pathology
|
| Street address |
172 Tongzipo Road
|
| City |
Changsha |
| State/province |
Hunan |
| ZIP/Postal code |
410011 |
| Country |
China |
| |
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| Platforms (1) |
| GPL18402 |
Agilent-046064 Unrestricted_Human_miRNA_V19.0_Microarray (miRNA ID version) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA252815 |
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