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Series GSE57423 Query DataSets for GSE57423
Status Public on May 14, 2014
Title Expression data from embryonic day 15.5 atrioventricular canal regions were isolated from Scx-/- and Scx+/+ mice.
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Purpose: Our lab has previously shown that Scleraxis (Scx) is require for proper valve development in vivo. In order to fully explore gene networks regulated by Scx during the vital stages of valve remodeling , high throughput RNA-squencing was performed.
Results:There were a total of 18,810 genes were detected. A total of 864 genes were differentially expressed Scx null AVC regions: 645 being upregulated and 217 downregulated.
 
Overall design In this data set, we include expression data from atrioventricular canal (AVC) regions from Scx null and wild-type littermate controls at embryonic day 15.5. A total of 6 samples were analyzed; 3 valve regions from E15.5 Scx-/- mice, and 3 from E15.5 Scx+/+ wild-type littermate controls. Differential expression read counts are ranked based on p-value (<0.05).
 
Contributor(s) Lincoln J, Barnette DN
Citation(s) 24983472
Submission date May 07, 2014
Last update date May 15, 2019
Contact name Damien Barnette
E-mail(s) Damien.Barnette@dpag.ox.ac.uk
Organization name University of Oxford
Street address Sherrington Building
City Oxford
State/province Oxfordshire
ZIP/Postal code OX12DF
Country United Kingdom
 
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (6)
GSM1382395 m15.5 AVC Scx Null1
GSM1382396 m15.5 AVC Scx Null2
GSM1382397 m15.5 AVC Scx Null3
Relations
BioProject PRJNA246425
SRA SRP041767

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE57423_RPKM_and_statistical_analysis.xlsx.gz 3.6 Mb (ftp)(http) XLSX
GSE57423_RPKM_only.txt.gz 674.5 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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