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Status |
Public on May 14, 2014 |
Title |
Expression data from embryonic day 15.5 atrioventricular canal regions were isolated from Scx-/- and Scx+/+ mice. |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Purpose: Our lab has previously shown that Scleraxis (Scx) is require for proper valve development in vivo. In order to fully explore gene networks regulated by Scx during the vital stages of valve remodeling , high throughput RNA-squencing was performed. Results:There were a total of 18,810 genes were detected. A total of 864 genes were differentially expressed Scx null AVC regions: 645 being upregulated and 217 downregulated.
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Overall design |
In this data set, we include expression data from atrioventricular canal (AVC) regions from Scx null and wild-type littermate controls at embryonic day 15.5. A total of 6 samples were analyzed; 3 valve regions from E15.5 Scx-/- mice, and 3 from E15.5 Scx+/+ wild-type littermate controls. Differential expression read counts are ranked based on p-value (<0.05).
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Contributor(s) |
Lincoln J, Barnette DN |
Citation(s) |
24983472 |
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Submission date |
May 07, 2014 |
Last update date |
May 15, 2019 |
Contact name |
Damien Barnette |
E-mail(s) |
Damien.Barnette@dpag.ox.ac.uk
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Organization name |
University of Oxford
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Street address |
Sherrington Building
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City |
Oxford |
State/province |
Oxfordshire |
ZIP/Postal code |
OX12DF |
Country |
United Kingdom |
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Platforms (1) |
GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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Samples (6)
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Relations |
BioProject |
PRJNA246425 |
SRA |
SRP041767 |