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| Status |
Public on Apr 15, 2015 |
| Title |
Molecular and Histological Characterization of Age Spots |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
In this study, we used immunohistochemical analysis and microarray analysis to investigate the mechanism underlying the development of age spots, focusing on the expression of specific markers associated with the functions and proliferation of melanocytes and keratinocytes
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| Overall design |
10 subjects of phototypes I or II (all female, age = 53-70) with various sizes and colors of age spots on their forearms were recruited for the study. Four mm whole skin punch biopsies were taken from age spots on the forearm of each subject and from a perilesional control area in the vicinity of each age spot.
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| Contributor(s) |
Choi W, Yin L, Smuda C, Mahns A, Kolbe L, Hearing VJ |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Apr 25, 2014 |
| Last update date |
Jan 23, 2019 |
| Contact name |
Vincent J. Hearing |
| Organization name |
National Cancer Institute
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| Street address |
BG 37 RM 2132B 37 CONVENT DR
|
| City |
BETHESDA |
| State/province |
MD |
| ZIP/Postal code |
20814 |
| Country |
USA |
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| Platforms (1) |
| GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA247971 |
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