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Series GSE55520 Query DataSets for GSE55520
Status Public on Jun 24, 2015
Title An analysis fo genomic structural alterations in iPS cells derived from xeroderma pigmentosum patients
Organism Homo sapiens
Experiment type Genome variation profiling by SNP array
SNP genotyping by SNP array
Summary To elucidate frequencies of genomic structural alterations, we performed an analysis using a SNP genotyping array (Illumina HumanCytoSNP-12 v2.1 DNA Analysis BeadChip Kit) for iPS cells derived from xeroderma pigmentosum patients (XP3OS, XP40OS, and XPEMB-1). Samples were collected after 10 to 25 passages to detect structural mutations occurred during the cell cultivation processes. Our results suggested a higher mutation rate of the iPS cells compared to those from normal cells.
Overall design The iPS-cell samples were collected after several passages togerther with their precursor cell samples and subjected to the SNP genotyping array. We searched for structural mutations occurred during the culture of the iPS cells.
Contributor(s) Nakabayashi K, Okamura K, Takahashi Y, Hata K, Umezawa A
Citation(s) 27197874, 31455402, 26697316
Submission date Mar 03, 2014
Last update date Oct 18, 2019
Contact name Akihiro Umezawa
Phone 81-3-5494-7047
Organization name National Center for Child Health and Development
Department Center for Regenerative Medicine
Street address 2-10-1 Okura
City Setagaya-ku
State/province Tokyo
ZIP/Postal code 157-8535
Country Japan
Platforms (1)
GPL13829 Illumina HumanCytoSNP-12 v2.1 BeadChip
Samples (6)
GSM1338611 XP3OS
GSM1338612 XP3OS iPS1 at passage 25
GSM1338613 XP40OS
BioProject PRJNA239827

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE55520_signal_intensities.txt.gz 24.4 Mb (ftp)(http) TXT
Processed data included within Sample table

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