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| Status |
Public on Apr 09, 2014 |
| Title |
Expression data of A2EN cells during early stage of Chlamydia trachomatis infection |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Chlamydia trachomatis is an obligate intracellular pathogen that causes trachoma and sextually transmitted disease in human. During early stage of infection, Chlamydia secreted bacterial effector proteins into host cell cytoplasm to help its entry and estabilishment of early replicated niche.
We identified a Chlamydia mutant that lack an early Effector. To address the function of this effector, we infected A2EN cells with this mutant (G1V) and its complemented counterpart (G1TEPP) to see what host gene transcriptions are affected by this effector.
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| |
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| Overall design |
A2EN cells were mock infected, or infected with a Chlamydia mutant or its complemented counterpart for 4 hour post infection.
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| |
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| Contributor(s) |
Carpenter VK, Chen Y |
| Citation(s) |
24586162 |
| |
| Submission date |
Jan 23, 2014 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Raphael H Valdivia |
| E-mail(s) |
raphael.valdivia@duke.edu
|
| Phone |
9196683831
|
| Organization name |
Duke University
|
| Department |
Molecular Genetics and Microbiology
|
| Lab |
Valdivia
|
| Street address |
207 Research drive, Jones bldg 272
|
| City |
Durham |
| State/province |
NC |
| ZIP/Postal code |
27710 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
|
| Samples (6)
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| Relations |
| BioProject |
PRJNA236228 |
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