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Status |
Public on Nov 28, 2013 |
Title |
Genes related to allergen avoidance in allergic rhinitis mouse model |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Allergen exposure was thought to play a critical role in the etiology of AR. And allergen avoidance, the practice of avoiding exposure to allergens, has been generally advised as the management of AR. However, the effect is uncertain and the underlying mechanism is far from known. We used gene expression microarrays to identify genes differentially regulated by allergen avoidance in allergic rhinitis mouse model.
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Overall design |
Affymetrix Mouse Gene 1.0 ST arrays were used to identify the expression profiling of nasal mucosa in three groups of mice: (1) mice sensitized and challenged with saline (control group); (2) mice sensitized and challenged with ovalbumin (OVA) and sacrificed 2 hours after the last challenge (OVA group); (3) mice sensitized and challenged with OVA and sacrificed 4 weeks after the last challenge (4w-after group).
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Contributor(s) |
Wang M, Yang J, Zhang L |
Citation missing |
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Submission date |
Nov 27, 2013 |
Last update date |
Mar 04, 2019 |
Contact name |
wang min |
E-mail(s) |
wang_min74@hotmail.com
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Organization name |
Beijing Institute of Otolaryngology
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Lab |
Beijing Institute of Otolaryngology
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Street address |
No. 17, HouGouHuTong, DongCheng District
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City |
Beijing |
State/province |
Beijing |
ZIP/Postal code |
Beijing 100005 |
Country |
China |
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Platforms (1) |
GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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Samples (9)
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Relations |
BioProject |
PRJNA230110 |