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| Status |
Public on Nov 23, 2013 |
| Title |
Expression data from mDCT cell-line over-expressing hMR |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Target gene of mineralocorticoid receptor (MR) is comparatively unknown, although distal convoluted tubule (DCT) expresses MR in in vivo.
We used microarray and immortalized murine DCT cell-line overexpressing human MR with treatment of aldosterone to elucidate target genes of MR in DCT.
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| Overall design |
mDCT overexpresses human MR by lipofection and is treated for 3 hours with ethanol (g1), or 10^-9 M aldosterone (g2), or 10^-7 M aldosterone (g3), or 10^-7 M aldosterone with pretreatment of 5 x 10^-6 M spironolactone (g4) for 2 hours.
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| Citation(s) |
24491541 |
| |
| Submission date |
Nov 23, 2013 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Kohei Ueda |
| Organization name |
The University of Tokyo
|
| Street address |
7-3-1, Hongo
|
| City |
Tokyo |
| ZIP/Postal code |
113-0033 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA229798 |
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