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Series GSE52636 Query DataSets for GSE52636
Status Public on Dec 31, 2013
Title The effect of a novel form of macrophage colony-stimulating factor (CSF1-Fc) on gene expression in the liver.
Organism Mus musculus
Experiment type Expression profiling by array
Summary Treatment of mice with daily injections of CSF1-Fc produce a 50% increase in the size of the liver within 5 days. There was extensive proliferation of hepatocytes, similar to that seen following partial hepatectomy.
Overall design Comparative gene expression profiles of the treated and control livers, alongside macrophages grown in CSF1, indicate extensive infiltration by macrophages in response to CSF1-Fc, and demonstrate that infiltrating macrophages produced several candidate mediators of hepatocyte proliferation.
Contributor(s) Gow DJ, Sauter KA, Hume DA
Citation(s) 24962162
Submission date Nov 21, 2013
Last update date Jan 08, 2020
Contact name Kristin Sauter
Organization name Roslin Institute/The University of Edinburgh
Street address Easter Bush, Midlothian
City Roslin
ZIP/Postal code EH25 9RG
Country United Kingdom
Platforms (1)
GPL11533 [MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version]
Samples (5)
GSM1273192 Control mouse liver sample replicate 1
GSM1273193 Control mouse liver sample replicate 2
GSM1273194 CSF1-Fc treated mouse liver sample replicate 1
BioProject PRJNA229512

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE52636_RAW.tar 20.0 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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