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| Status |
Public on Dec 01, 2013 |
| Title |
Transcriptional responses of mantle cell lymphoma (MCL) after NIK knockdown |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
MCL lines were treated with or without 100ng/ml doxycycline for 7 days
This experiment is designed to see if shRNA-mediated knockdown of NIK downregulates NFKB signaling in MCL lines with mutations in upstream regulators of the alternative pathway (TRAF2 & TRAF3)
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| Overall design |
MCL cells carrying inducible non-targeting control (NTC) shRNA, NIKshRNA#1 (NIKsh#1), or NIKshRNA#2 (NIKsh#2) were seeded in 6well dishes and treated for 7 days with or without 100ng/ml doxycycline.
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| Contributor(s) |
Rahal R, Korn JM |
| Citation(s) |
24362935 |
| |
| Submission date |
Nov 15, 2013 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Joshua M Korn |
| E-mail(s) |
joshkorn@gmail.com
|
| Organization name |
Novartis
|
| Street address |
250 Mass Ave
|
| City |
Cambridge |
| State/province |
MA |
| ZIP/Postal code |
02141 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA228923 |
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