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Series GSE5135 Query DataSets for GSE5135
Status Public on Jun 29, 2006
Title Hematopoietic stem cells treated with the Notch ligand Delta 4 HSC_notch_IGR
Platform organisms Mus musculus; Rattus norvegicus
Sample organism Mus musculus
Experiment type Expression profiling by array
Summary The Notch pathway regulates cell-fate decisions in a wide variety of cell types, often inhibiting particular differentiation programs and permitting either self-renewal or differentiation along alternate pathways. Notch receptors and Notch ligands have been found on hematopoietic stem cells (HSC) or marrow stromal cells. In the present study, through a microarray approach, we analyzed the gene expression variations from cultured murine HSC with or without a Notch ligand Delta4 at 6 hours, 12 hours and 24 hours after the induction of the Notch pathway.
Keywords: time course
 
Overall design 13 samples against a common reference.
two dye swap for each condition.
 
Citation(s) 25460604
Submission date Jun 23, 2006
Last update date Mar 18, 2015
Contact name Cyril Catelain
E-mail(s) ccatelain@igr.fr
Phone 0142114233
Fax 0142115240
Organization name INSERM
Lab U790
Street address 39, rue Camille Desmoulins
City Villejuif
ZIP/Postal code 94805
Country France
 
Platforms (2)
GPL3890 CEA - DSV/DRR/SGF : APV Mouse and Rat 23k
GPL3891 CEA - DSV/DRR/SGF : APZ Mouse and Rat 23k
Samples (52)
GSM115966 Delta4 ligand treatment for 24 hours APV007
GSM115967 Delta4 ligand treatment for 24 hours APV008
GSM115968 Delta4 ligand treatment for 24 hours APV009
Relations
BioProject PRJNA96645

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