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Series GSE50566 Query DataSets for GSE50566
Status Public on Jul 26, 2016
Title Homeostatic skin contains two different subsets of resident macrophages with distinct origin and gene profile.
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We have found the existence of two independent populations contributing to the skin-resident macrophage pool based on their different origin. We have analyzed their gene profile by deep-sequencing (RNA-Seq). Analysis of RNA-Seq data revealed a differential expression signature between both subsets of skin macrophages for 744 of 17741 genes compiled (198 of them showing similar normalized expression levels across replicates). We have further characterized their specialized functions related to their different gene profiles.
Overall design Examination of gene profile of 2 different macrophage subsets coexisting in skin under steady state.
Contributor(s) Sánchez-Madrid F, Barreiro O
Citation(s) 27304075
Submission date Sep 04, 2013
Last update date May 15, 2019
Contact name Francisco Sanchez-Madrid
Organization name Hospital Universitario de la Princesa
Street address Diego de Leon 62
City Madrid
ZIP/Postal code 28006
Country Spain
Platforms (1)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
Samples (4)
GSM1223649 Ly5.1 macrophages rep1
GSM1223650 Ly5.1 macrophages rep2
GSM1223651 Ly5.2 macrophages rep1
BioProject PRJNA217956
SRA SRP029466

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Supplementary file Size Download File type/resource
GSE50566_OB_fpkm_table.csv.gz 285.1 Kb (ftp)(http) CSV
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Raw data are available in SRA

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