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| Status |
Public on Aug 09, 2019 |
| Title |
Direct conversion of adult skin fibroblasts to endothelial cells by defined factors |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
We directly converted mouse adult skin fibroblasts (SFBs) into induced endothelial cells (iECs) by transduction of 5 key factors.
We analyzed the genome-wide gene expression profile of iECs, and compared it with those of negative controls (original SFBs, mock-infected SFBs) or those of positive controls (primary endothelial cells from lungs of mice, MS-1 endothelial cell line).
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| Overall design |
12 total samples were analyzed.
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| Contributor(s) |
Han J, Chang S, Cho H, Choi S, Ahn H, Lee J, Jeong H, Youn S, Lee H, Kwon Y, Cho H, Oh B, Oettgen P, Park Y, Kim H |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Aug 21, 2013 |
| Last update date |
Aug 09, 2019 |
| Contact name |
Jung-Kyu Han |
| E-mail(s) |
hpcrates@gmail.com
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| Phone |
82-2-2072-4870
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| Organization name |
Seoul National University Hospital
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| Department |
Internal Medicine
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| Street address |
101 Daehak-ro, Jongro-gu,
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| City |
Seoul |
| ZIP/Postal code |
110-744 |
| Country |
South Korea |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (12)
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| GSM1213512 |
mock-infected skin fibroblast, biological rep2 |
| GSM1213513 |
mock-infected skin fibroblast, biological rep3 |
| GSM1213514 |
induced endothelial cells, biological rep1 |
| GSM1213515 |
induced endothelial cells, biological rep2 |
| GSM1213516 |
induced endothelial cells, biological rep3 |
| GSM1213517 |
primary endothelial cells from mouse lungs, biological rep1 |
| GSM1213518 |
primary endothelial cells from mouse lungs, biological rep2 |
| GSM1213519 |
MS-1 endothelial cell line, biological rep1 |
| GSM1213520 |
MS-1 endothelial cell line, biological rep2 |
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| Relations |
| BioProject |
PRJNA215936 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE50071_RAW.tar |
54.1 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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