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Series GSE50000 Query DataSets for GSE50000
Status Public on Feb 15, 2014
Title SM003 - icSARS CoV, SARS MA15 wild type and SARS BatSRBD mutant virus infections of C57BL6 mice - A time course
Organism Mus musculus
Experiment type Expression profiling by array
Summary This purpose of this experiment was to investigate the transcriptional differences between mice infected with icSARS CoV, SARS MA15 wild type or SARS BatSRBD viruses.
Overall design Overview of Experiment: Groups of 20 week old C57BL6 mice were infected with icSARS CoV, Wild Type SARS MA15 or SARS BatSRBD mutant viruses. Infections were done at 10^4 PFU or 10^5 PFU or time-matched mock infected. Time points were 1, 2, 4 and 7 d.p.i. There were 3-5 animals/dose/time point. Lung samples were collected for virus load, transcriptional and proteomics analysis. Weight loss and animal survival were also monitored.
Contributor(s) Katze M, Baric R, Law L, Gralinski L, Chang J
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Submission date Aug 19, 2013
Last update date Jan 12, 2017
Contact name Michael Katze
Organization name University of Washington
Department Microbiology
Lab Michael G. Katze, Ph.D
Street address Rosen Building 960 Republican St.
City Seattle
State/province WA
ZIP/Postal code 98109-4325
Country USA
Platforms (1)
GPL7202 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)
Samples (86)
GSM1211755 SM003_10^4_MA15_d1_1
GSM1211756 SM003_10^4_MA15_d1_2
GSM1211757 SM003_10^4_MA15_d1_3
BioProject PRJNA215773

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE50000_RAW.tar 751.3 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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