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| Status |
Public on Jul 07, 2006 |
| Title |
Expression data from NOD-scid vs B6-scid pancreas, submandibular glands, & lacrimal glands |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Prior to the onset of autoimmune destruction, type 1 diabetic patients and an animal model thereof, the nonobese diabetic (NOD) mouse, show morphological and functional abnormalities in target organs, which may act as inciting events for leukocyte infiltration. To better understand these abnormalities, but without the complications associated with inflammatory infiltrates, we examined genes expressed in autoimmune target tissues (pancreas, submandibular glands, and lacrimal glands) of NOD/scid mice and of autoimmune-resistant C57BL6/scid mice.
Keywords: tissue expression, disease prone versus resistant strain comparison
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| Overall design |
Pancreata (6 weeks old mice), submandibular (9 and 15 weeks), and lacrimal glands (15 weeks) from individual NOD-scid and B6-scid mice were isolated for RNA extraction and hybridization on Affymetrix microarrays.
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| Contributor(s) |
Chaparro RJ, Konigshofer Y, Beilhack GF, Shizuru JA, McDevitt HO, Chien Y |
| Citation(s) |
16895987 |
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| Submission date |
May 30, 2006 |
| Last update date |
Feb 18, 2018 |
| Contact name |
Rodolfo Chaparro |
| Organization name |
Albert Einstein College of Medicine
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| Department |
Microbiology and Immunology
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| Lab |
Golding Building, Room 105
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| Street address |
1300 Morris Park Avenue
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| City |
Bronx |
| State/province |
NY |
| ZIP/Postal code |
10461 |
| Country |
USA |
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| Platforms (3) |
| GPL81 |
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array |
| GPL82 |
[MG_U74Bv2] Affymetrix Murine Genome U74B Version 2 Array |
| GPL83 |
[MG_U74Cv2] Affymetrix Murine Genome U74 Version 2 Array |
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| Samples (117)
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| GSM111294 |
a C57BL/6-scid female, 6 week pancreas, replicate 1 |
| GSM111295 |
a C57BL/6-scid female, 6 week pancreas, replicate 2 |
| GSM111296 |
a C57BL/6-scid female, 6 week pancreas, replicate 3 |
| GSM111297 |
a C57BL/6-scid female, 6 week pancreas, replicate 4 |
| GSM111298 |
a C57BL/6-scid female, 6 week pancreas, replicate 5 |
| GSM111299 |
a NOD-scid female, 6 week pancreas, replicate 1 |
| GSM111300 |
a NOD-scid female, 6 week pancreas, replicate 2 |
| GSM111301 |
a NOD-scid female, 6 week pancreas, replicate 3 |
| GSM111302 |
a NOD-scid female, 6 week pancreas, replicate 4 |
| GSM111303 |
a NOD-scid female, 6 week pancreas, replicate 5 |
| GSM111304 |
a C57BL/6-scid female, 9 week submandibular gland, replicate 1 |
| GSM111305 |
a C57BL/6-scid female, 9 week submandibular gland, replicate 2 |
| GSM111306 |
a C57BL/6-scid female, 9 week submandibular gland, replicate 3 |
| GSM111307 |
a C57BL/6-scid female, 9 week submandibular gland, replicate 4 |
| GSM111308 |
a C57BL/6-scid female, 9 week submandibular gland, replicate 5 |
| GSM111309 |
a NOD-scid female, 9 week submandibular gland, replicate 1 |
| GSM111310 |
a NOD-scid female, 9 week submandibular gland, replicate 2 |
| GSM111311 |
a NOD-scid female, 9 week submandibular gland, replicate 3 |
| GSM111312 |
a NOD-scid female, 9 week submandibular gland, replicate 4 |
| GSM111313 |
a NOD-scid female, 9 week submandibular gland, replicate 5 |
| GSM111314 |
a C57BL/6-scid female, 15 week submandibular gland, replicate 1 |
| GSM111315 |
a C57BL/6-scid female, 15 week submandibular gland, replicate 2 |
| GSM111316 |
a C57BL/6-scid female, 15 week submandibular gland, replicate 3 |
| GSM111317 |
a C57BL/6-scid female, 15 week submandibular gland, replicate 4 |
| GSM111318 |
a C57BL/6-scid female, 15 week submandibular gland, replicate 5 |
| GSM111319 |
a NOD-scid female, 15 week submandibular gland, replicate 1 |
| GSM111320 |
a NOD-scid female, 15 week submandibular gland, replicate 2 |
| GSM111321 |
a NOD-scid female, 15 week submandibular gland, replicate 3 |
| GSM111322 |
a NOD-scid female, 15 week submandibular gland, replicate 4 |
| GSM111323 |
a NOD-scid female, 15 week submandibular gland, replicate 5 |
| GSM111324 |
a C57BL/6-scid female, 15 week lacrimal gland, replicate 1 |
| GSM111325 |
a C57BL/6-scid female, 15 week lacrimal gland, replicate 2 |
| GSM111326 |
a C57BL/6-scid female, 15 week lacrimal gland, replicate 3 |
| GSM111327 |
a C57BL/6-scid female, 15 week lacrimal gland, replicate 4 |
| GSM111328 |
a C57BL/6-scid female, 15 week lacrimal gland, replicate 5 |
| GSM111329 |
a NOD-scid female, 15 week lacrimal gland, replicate 1 |
| GSM111330 |
a NOD-scid female, 15 week lacrimal gland, replicate 2 |
| GSM111331 |
a NOD-scid female, 15 week lacrimal gland, replicate 3 |
| GSM111332 |
a NOD-scid female, 15 week lacrimal gland, replicate 4 |
| GSM111333 |
b C57BL/6-scid female, 6 week pancreas, replicate 1 |
| GSM111334 |
b C57BL/6-scid female, 6 week pancreas, replicate 2 |
| GSM111335 |
b C57BL/6-scid female, 6 week pancreas, replicate 3 |
| GSM111336 |
b C57BL/6-scid female, 6 week pancreas, replicate 4 |
| GSM111337 |
b C57BL/6-scid female, 6 week pancreas, replicate 5 |
| GSM111338 |
b NOD-scid female, 6 week pancreas, replicate 1 |
| GSM111339 |
b NOD-scid female, 6 week pancreas, replicate 2 |
| GSM111340 |
b NOD-scid female, 6 week pancreas, replicate 3 |
| GSM111341 |
b NOD-scid female, 6 week pancreas, replicate 4 |
| GSM111342 |
b NOD-scid female, 6 week pancreas, replicate 5 |
| GSM111343 |
b C57BL/6-scid female, 9 week submandibular gland, replicate 1 |
| GSM111344 |
b C57BL/6-scid female, 9 week submandibular gland, replicate 2 |
| GSM111345 |
b C57BL/6-scid female, 9 week submandibular gland, replicate 3 |
| GSM111346 |
b C57BL/6-scid female, 9 week submandibular gland, replicate 4 |
| GSM111347 |
b C57BL/6-scid female, 9 week submandibular gland, replicate 5 |
| GSM111348 |
b NOD-scid female, 9 week submandibular gland, replicate 1 |
| GSM111349 |
b NOD-scid female, 9 week submandibular gland, replicate 2 |
| GSM111350 |
b NOD-scid female, 9 week submandibular gland, replicate 3 |
| GSM111351 |
b NOD-scid female, 9 week submandibular gland, replicate 4 |
| GSM111352 |
b NOD-scid female, 9 week submandibular gland, replicate 5 |
| GSM111353 |
b C57BL/6-scid female, 15 week submandibular gland, replicate 1 |
| GSM111354 |
b C57BL/6-scid female, 15 week submandibular gland, replicate 2 |
| GSM111355 |
b C57BL/6-scid female, 15 week submandibular gland, replicate 3 |
| GSM111356 |
b C57BL/6-scid female, 15 week submandibular gland, replicate 4 |
| GSM111357 |
b C57BL/6-scid female, 15 week submandibular gland, replicate 5 |
| GSM111358 |
b NOD-scid female, 15 week submandibular gland, replicate 1 |
| GSM111359 |
b NOD-scid female, 15 week submandibular gland, replicate 2 |
| GSM111360 |
b NOD-scid female, 15 week submandibular gland, replicate 3 |
| GSM111361 |
b NOD-scid female, 15 week submandibular gland, replicate 4 |
| GSM111362 |
b NOD-scid female, 15 week submandibular gland, replicate 5 |
| GSM111363 |
b C57BL/6-scid female, 15 week lacrimal gland, replicate 1 |
| GSM111364 |
b C57BL/6-scid female, 15 week lacrimal gland, replicate 2 |
| GSM111365 |
b C57BL/6-scid female, 15 week lacrimal gland, replicate 3 |
| GSM111366 |
b C57BL/6-scid female, 15 week lacrimal gland, replicate 4 |
| GSM111367 |
b C57BL/6-scid female, 15 week lacrimal gland, replicate 5 |
| GSM111368 |
b NOD-scid female, 15 week lacrimal gland, replicate 1 |
| GSM111369 |
b NOD-scid female, 15 week lacrimal gland, replicate 2 |
| GSM111370 |
b NOD-scid female, 15 week lacrimal gland, replicate 3 |
| GSM111371 |
b NOD-scid female, 15 week lacrimal gland, replicate 4 |
| GSM111372 |
c C57BL/6-scid female, 6 week pancreas, replicate 1 |
| GSM111373 |
c C57BL/6-scid female, 6 week pancreas, replicate 2 |
| GSM111374 |
c C57BL/6-scid female, 6 week pancreas, replicate 3 |
| GSM111375 |
c C57BL/6-scid female, 6 week pancreas, replicate 4 |
| GSM111376 |
c C57BL/6-scid female, 6 week pancreas, replicate 5 |
| GSM111377 |
c NOD-scid female, 6 week pancreas, replicate 1 |
| GSM111378 |
c NOD-scid female, 6 week pancreas, replicate 2 |
| GSM111379 |
c NOD-scid female, 6 week pancreas, replicate 3 |
| GSM111380 |
c NOD-scid female, 6 week pancreas, replicate 4 |
| GSM111381 |
c NOD-scid female, 6 week pancreas, replicate 5 |
| GSM111382 |
c C57BL/6-scid female, 9 week submandibular gland, replicate 1 |
| GSM111383 |
c C57BL/6-scid female, 9 week submandibular gland, replicate 2 |
| GSM111384 |
c C57BL/6-scid female, 9 week submandibular gland, replicate 3 |
| GSM111385 |
c C57BL/6-scid female, 9 week submandibular gland, replicate 4 |
| GSM111386 |
c C57BL/6-scid female, 9 week submandibular gland, replicate 5 |
| GSM111387 |
c NOD-scid female, 9 week submandibular gland, replicate 1 |
| GSM111388 |
c NOD-scid female, 9 week submandibular gland, replicate 2 |
| GSM111389 |
c NOD-scid female, 9 week submandibular gland, replicate 3 |
| GSM111390 |
c NOD-scid female, 9 week submandibular gland, replicate 4 |
| GSM111391 |
c NOD-scid female, 9 week submandibular gland, replicate 5 |
| GSM111392 |
c C57BL/6-scid female, 15 week submandibular gland, replicate 1 |
| GSM111393 |
c C57BL/6-scid female, 15 week submandibular gland, replicate 2 |
| GSM111394 |
c C57BL/6-scid female, 15 week submandibular gland, replicate 3 |
| GSM111395 |
c C57BL/6-scid female, 15 week submandibular gland, replicate 4 |
| GSM111396 |
c C57BL/6-scid female, 15 week submandibular gland, replicate 5 |
| GSM111397 |
c NOD-scid female, 15 week submandibular gland, replicate 1 |
| GSM111398 |
c NOD-scid female, 15 week submandibular gland, replicate 2 |
| GSM111399 |
c NOD-scid female, 15 week submandibular gland, replicate 3 |
| GSM111400 |
c NOD-scid female, 15 week submandibular gland, replicate 4 |
| GSM111401 |
c NOD-scid female, 15 week submandibular gland, replicate 5 |
| GSM111402 |
c C57BL/6-scid female, 15 week lacrimal gland, replicate 1 |
| GSM111403 |
c C57BL/6-scid female, 15 week lacrimal gland, replicate 2 |
| GSM111404 |
c C57BL/6-scid female, 15 week lacrimal gland, replicate 3 |
| GSM111405 |
c C57BL/6-scid female, 15 week lacrimal gland, replicate 4 |
| GSM111406 |
c C57BL/6-scid female, 15 week lacrimal gland, replicate 5 |
| GSM111407 |
c NOD-scid female, 15 week lacrimal gland, replicate 1 |
| GSM111408 |
c NOD-scid female, 15 week lacrimal gland, replicate 2 |
| GSM111409 |
c NOD-scid female, 15 week lacrimal gland, replicate 3 |
| GSM111410 |
c NOD-scid female, 15 week lacrimal gland, replicate 4 |
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| Relations |
| BioProject |
PRJNA95501 |
| Supplementary data files not provided |
| Processed data included within Sample table |
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