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Status |
Public on Jul 17, 2024 |
Title |
Adenoviral Transduction of ARL11 in NHU-hTERT cells |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Analyses of the whole genome mRNA gene expression profiling performed on ARL11-transducted normal urothelium cells. The results revealed that TP53, RB1 and CDKN2A pathways were activated and the E2F1 and MYC pathways were inhibited in cells expressing ARL11. ARL11-transducted cells also inhibited RAS pathway activation.
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Overall design |
Total RNA was extracted from NHU-hTERT cells transducted with ARL11 and cells with empty vector
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Contributor(s) |
Lee S, Czerniak B, Majewski T |
Citation missing |
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Submission date |
Jul 18, 2013 |
Last update date |
Jul 17, 2024 |
Contact name |
Bogdan Czerniak |
E-mail(s) |
bczernia@mdanderson.org
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Organization name |
UT MD Anderson Cancer Center
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Department |
Pathology
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Street address |
1515 Holcombe
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City |
Houston |
State/province |
TX |
ZIP/Postal code |
77030 |
Country |
USA |
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Platforms (1) |
GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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Samples (6)
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GSM1192473 |
NHU-hTERT cells with empty vector Adeno A |
GSM1192474 |
NHU-hTERT cells with empty vector Adeno B |
GSM1192475 |
NHU-hTERT cells with empty vector Adeno C |
GSM1192476 |
ARL11 Adenoviral Transducted NHU-hTERT cells after 48 hours A |
GSM1192477 |
ARL11 Adenoviral Transducted NHU-hTERT cells after 48 hours B |
GSM1192478 |
ARL11 Adenoviral Transducted NHU-hTERT cells after 48 hours C |
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Relations |
BioProject |
PRJNA213160 |