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Status |
Public on Jul 16, 2013 |
Title |
Expression analysis of mock- or RAD21-transduced Kasumi1 cells |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
We recently identified recurrent mutations of cohesin complex in myeloid neoplasms through whole-exome sequencing analysis. RAD21 is one of the main components of the cohesin complex. In this study, to investigate the biological impact of wild-type RAD21 on Kasumi1 cells harboring RAD21 mutation, Kasumi1 cells were retrovirally transduced with either mock or wild-type RAD21, and expression array was performed.
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Overall design |
Expression analysis was performed for mock- or wild-type RAD21-transduced Kasumi-1 cells in triplicate. The experiment was performed twice independently.
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Contributor(s) |
Kon A, Sanada M, Sato-Otsubo A, Yoshida K, Nagata Y, Sato Y, Ogawa S |
Citation(s) |
23955599 |
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Submission date |
Jun 04, 2013 |
Last update date |
Mar 25, 2019 |
Contact name |
Ayana Kon |
E-mail(s) |
akon-tky@umin.ac.jp
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Organization name |
The University of Tokyo
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Department |
Cancer Genomics Project
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Street address |
Hongo 7-3-1, Bunkyo-ku
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City |
Tokyo |
ZIP/Postal code |
113-8655 |
Country |
Japan |
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Platforms (1) |
GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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Samples (12)
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This SubSeries is part of SuperSeries: |
GSE47684 |
Recurrent mutations of multiple components of cohesin complex in myeloid neoplasms |
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Relations |
BioProject |
PRJNA207003 |