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Series GSE46988 Query DataSets for GSE46988
Status Public on Oct 16, 2013
Title Expression data from rat spinal cord injury and mesenchymal stromal cells (MSC) or olfactory ensheathing cells (OEC) transplantation
Organism Rattus norvegicus
Experiment type Expression profiling by array
Summary We analyzed the changes in the spinal cord transcriptome after a spinal cord contusion injury and MSC or OEC transplantation. The cells were injected immediately or 7 days after the injury. The mRNA of the spinal cord injured segment was extracted and analyzed by microarray at 2 and 7 days after cell grafting.
 
Overall design 52 total samples were analyzed in 13 different groups. Each group include 4 samples and each one were analyzed as a biological replica. The intact animals were used as control of injury. The vehicle (VHC) groups were used as control of transplantation procedure. The MSC or OEC graft were injected at the day of injury (acute graft) or seven days after injury (delayed graft). The samples from engrafted animals were obtained at 2 or 7 days after cell transplantation. To determine the effects of MSC or OEC transplantation, the expression value of each engrafted sample were compared with correspondent VHC group.
 
Contributor(s) Torres-Espín A, Hernández J, Navarro X
Citation(s) 24146830
Submission date May 15, 2013
Last update date Mar 14, 2017
Contact name Xavier Navarro
E-mail(s) xavier.navarro@uab.cat
Organization name Univarsitat Autònoma de Barcelona
Street address Edif. M, Campus UAB
City Bellaterra
ZIP/Postal code E-08193
Country Spain
 
Platforms (1)
GPL11534 [RaGene-1_1-st] Affymetrix Rat Gene 1.1 ST Array [transcript (gene) version]
Samples (52)
GSM1142632 intact animal, biological rep1
GSM1142633 intact animal, biological rep2
GSM1142634 intact animal, biological rep3
Relations
BioProject PRJNA203304

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE46988_RAW.tar 229.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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