|
| Status |
Public on Aug 06, 2013 |
| Title |
FGFR2 Signaling Underlies p63 Oncogenic Function in Squamous Cell Carcinoma |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
This study was designed to examine the requirement for the p63 transcription factor in Squamous Cell Carcinoma (SCC) tumor maintenance in an in vivo murine system. A tamoxifen-inducible Keratin 14-driven Cre recombinase transgene was used to conditionally excise p63 in advanced murine SCC tumors. These data show the context-dependent regulation of p63 target genes in cancer.
|
| |
|
| Overall design |
Total RNA from murine Squamous Cell Carcinoma tumors was examined 1-3 days following genomic excision of TP63 in Keratin 14-expressing tumor cells.
|
| |
|
| Contributor(s) |
Ramsey MR, Ellisen LW |
| Citation(s) |
23867503 |
| |
| Submission date |
Apr 10, 2013 |
| Last update date |
Jan 16, 2019 |
| Contact name |
Matthew Ramsey |
| Organization name |
Brigham and Women's Hospital
|
| Department |
Dermatology
|
| Lab |
Matthew R. Ramsey
|
| Street address |
77 Ave Louis Pasteur, HIM 668
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA196677 |
Less...
More...