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Series GSE45531 Query DataSets for GSE45531
Status Public on Feb 04, 2014
Title Transcriptome profiling of T84 colorectal carcinoma cells treated with receptor guanylyl cyclace C agonist (stable toxin)
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Receptor guanylyl cyclase C (GC-C) is expressed in the intestinal epithelia and plays a key role in intestinal physiology. Activation of GC-C by its ligands has been shown to regulate proliferation and differentiation of enterocytes along the crypt-villus axis. This study aims to identify genes regulated by GC-C activation and elevation of cGMP in colorectal carcinoma cells. This will help understand the molecular targets and biological pathways regulated by GC-C to bring about cancer cell cytostasis.
Overall design ST (Cy5) Vs. Control (Cy3), ST (Cy5) Vs. Control (Cy3)
Contributor(s) Basu N, Visweswariah SS
Citation(s) 24217248
Submission date Mar 27, 2013
Last update date Feb 22, 2018
Contact name Sandhya S Visweswariah
Organization name Indian Institute of Science
Department Molecular Reproduction, Development and Genetics
Street address GA-09, Dept of MRDG, Biological Sciences Building, Indian Institute of Science
City Bangalore
State/province Karnataka
ZIP/Postal code 560012
Country India
Platforms (1)
GPL4133 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
Samples (2)
GSM1108102 T84_1h_ST_Rep1
GSM1108103 T84_1h_ST_Rep2
BioProject PRJNA194541

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE45531_RAW.tar 33.0 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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