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Series GSE45180 Query DataSets for GSE45180
Status Public on Dec 31, 2013
Title Gene expression data from CD11b-positive myeloid cells infiltrating tumors after local irradiation
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Analysis of global gene expression in myeloid cells infiltrating tumors after irradiation. Cell death induces recruitment of myeloid cells into irradiated tumors thereby stimulating tumor recurrence. Results provide insights into molecular mechanisms regulating tumorigenic functions of myeloid cells in tumors re-growing after radiation therapy.
 
Overall design Samples were collected at day 4 from irradiated tumors in WT, TLR9KO and Stat3KO (MxCre/Stat3flox). There were total 11 samples with  3-4 replicates of each sample type.
 
Contributor(s) Kortylewski M, Gao C, Kozlowska A, Li H
Citation(s) 24154870
Submission date Mar 14, 2013
Last update date May 15, 2019
Contact name Haiqing Li
E-mail(s) hali@coh.org
Phone 626-256-4673
Organization name Beckman Research Institute of City of Hope, Center for Informatics
Department Department of Computational & Quantitative Medicine
Lab Research Informatics
Street address 1500 East Duarte Road
City Duarte
State/province CA
ZIP/Postal code 91010
Country USA
 
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (11)
GSM1098599 STAT3KO Rep1
GSM1098600 STAT3KO Rep2
GSM1098601 STAT3KO Rep3
Relations
BioProject PRJNA193154
SRA SRP019455

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE45180_RAW.tar 1.1 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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