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Series GSE4342 Query DataSets for GSE4342
Status Public on Aug 31, 2006
Title Gefitinib sensitivity in NSCLC cell lines
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Eleven NSCLC cell lines with widely divergent gefitinib sensitivities were compared using gene expression. Genes associated with gefitinib response were used to classify additional NSCLC lines with unknown gefitnib sensitivity.
A subset of the test set data was tested for gefitinib sensitivity, and results correlated strongly with the gene expression-based predictions

All eleven training set lines, and seven test set lines had both HGU133A and B chips done, while other test set lines had only HGU133As.
Keywords: cell response comparison
Overall design Baseline (unstimulated) gene expression was measured in a large panel of NSCLC cell lines
Contributor(s) Coldren CD, Helfrich BA, Witta SE, Sugita M, Lapadat R, Zeng C, Barón A, Franklin WA, Hirsch FR, Minna JD, Geraci MW, Bunn PA Jr
Citation(s) 16877703, 19634903
Submission date Mar 06, 2006
Last update date Aug 20, 2019
Contact name Christopher D Coldren
Phone 303 724 6056
Organization name University of Colorado School of Medicine
Department Medicine
Lab Pulmonary Sciences and Critical Care Medicine
Street address 12700 East 17th Place
City Aurora
State/province CO
ZIP/Postal code 80045
Country USA
Platforms (2)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
GPL97 [HG-U133B] Affymetrix Human Genome U133B Array
Samples (63)
GSM98973 A549 U133A run at UCHSC
GSM98974 Calu3 U133A run at UCHSC
GSM98975 H125 U133A run at UCHSC
BioProject PRJNA94835

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Supplementary data files not provided

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