|
| Status |
Public on Mar 01, 2013 |
| Title |
Analysis of DNA methylation dynamics at Alu elements during human B cell activation |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by high throughput sequencing
|
| Summary |
Paired-end sequencing of methylated DNA fragments in B cell subsets revealed widespread loss of methylation at Alu elements upon B cell activation.
|
| |
|
| Overall design |
DNA methylation pattern was analyzed in purified naïve and germinal-center B cells derived from 1 patient
|
| |
|
| Contributor(s) |
Lai AY, Wade PA |
| Citation(s) |
24013550 |
| |
| Submission date |
Nov 19, 2012 |
| Last update date |
May 15, 2019 |
| Contact name |
Paul A Wade |
| E-mail(s) |
wadep2@niehs.nih.gov
|
| Phone |
919-541-3392
|
| Organization name |
NIEHS
|
| Department |
Laboratory of Molecular Carcinogenesis
|
| Street address |
111 TW Alexander Drive
|
| City |
Research Triangle Park |
| State/province |
NC |
| ZIP/Postal code |
27709 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10999 |
Illumina Genome Analyzer IIx (Homo sapiens) |
|
| Samples (2) |
|
| Relations |
| BioProject |
PRJNA181260 |
| SRA |
SRP017236 |
